Innate Response Formulas Vitamin D-3, 60 Tablets

Vitamin D-3 is a hormone that is naturally created by the skin with adequate sunlight (direct contact with the skin).The primary source of Vitamin D-3 is the sun. Vitamin D-3 is an important link to the sun’life sustaining benefits. Together their energy touches every aspect of the physiology. Vitamin D-3 in conjunction with the sun affects cellular development, cell growth, cellular functions, cell to cell communication, gene expression, immune function, energy metabolism, muscle strength and coordination, neurotransmitter production, some types of inflammatory response and bone development.

The Benefits of Vitamin D-3

Breakthrough research on Vitamin D-3’s health benefits has created great excitement in the nutrition community. There is extensive evidence that Vitamin D-3’s importance to health goes far beyond the best known benefit. Vitamin D-3’s expanding range of therapeutic benefits includes so much more than bone building and enhancing calcium utilization.

Vitamin D-3

Affects Muscle Strength and Coordination

Maintains Tissue Function

Affects Energy Production

Affects Immune Function

Affects Gene Expression Vitamin D-3 affects Cell Development, Cell Growth and Cell Function

Plays a role in Cell to Cell Communication

Has been shown to be effective in Depression Therapies

Has been shown to be effective in Autoimmune Disorder (MS) Therapies

Has been shown to be effective in Therapeutic Cancer Programs

Has been shown to be effective in Cancer Prevention Programs

Has been shown to be effective in Lung Health Therapies

Influences Nervous System Functions, central and peripheral, through its modulation of Neuronal Calcium

Is involved in the creation of neurotransmitters. Vitamin D-3 possesses
anti-inflammatory properties and has been shown to be effective in Rheumatoid Arthritis therapies.

Vitamin D-3 Deficiency Symptoms

Too little active Vitamin D-3 can lead to or be a contributing factor in psoriasis, osteoporosis, osteopenia, rickets, thyroid dysfunction, compromised immune function, hearing dysfunction, liver and kidney disorders, some forms of cancer, periodontal disease, cardiovascular disease and decreased insulin sensitivity.

Vitamin D-3 Deficiency Factors

Avoidance of exposure to the sun

Use of sunscreens that interfere with D-3 production in the skin (sunscreens over 8 SPF reduce vitamin D production by 95%)(ref.9)

Living in the North America especially on the Northern Coasts in the winter

The elderly develop deficiencies with less exposure to the sun on a daily basis

Aging diminishes Vitamin D synthesis

Limited vegetarian and raw food sources of vitamin D

Vitamin D in our food is degraded and catalyzed by light, heat and acids

Decreased liver and kidney function reduce the ability to convert vitamin D to its active form

Being overweight

Mal absorption and digestive problems create difficulty converting vitamin D from food or sun into its active form.

Low fat diets (healthy fats support vitamin D conversion and utilization)

Vitamin D deficiency status varies with latitude.

Dark Skin lessens vitamin D absorption through the skin, therefore African Americans are five times more likely to be deficient than Caucasians.

Vitamin D-3 Dosage

Current research shows that the physiology’requirements for Vitamin D-3 are higher than previously thought. Recent research indicates those who totally avoid the sun may require as much as 4,000 IU of Vitamin D-3 daily. It is estimated that 20 minutes of direct summer sunlight, unfiltered by clothing, glass or sunscreens, enables the body to manufacture about 20,000 IU of vitamin D. This is much higher than the RDI/RDA set by the government. More research is needed to understand our varying requirements. Exposure to sunlight is an important factor to consider. Supplementation with 400 to 1000 IU is becoming common. Vitamin D-3 nutritional requirements will vary according to sun exposure, age, diet, and health. Most multiple vitamin and mineral supplements have vitamin D at 100-400 IU.

Vitamin D-3 Sources

The importance of Vitamin D-3 to health reinforces the importance of moderate daily exposure to direct sunlight on our quality of life. People in many parts of North America and at different stages of life, have limited exposure to direct, unfiltered sunlight on their skin. Aging contributes to the decline of the manufacture of Vitamin D-3 in the body. Some areas of the country have cloudy days, rain, snow, and cold weather that encourage people to cover their skin or stay indoors. Fear of skin cancer has people using sunscreens and avoiding sunlight exposure. We need 10-20 minutes of direct, unfiltered sunlight on our skin, 3 or more times a week. This does not mean sunburn moderation is prudent. Those with darker skin produce less vitamin D in response to sunlight exposure. While some food is fortified with vitamin D (often in the less bio-available form D-2) obtaining adequate quantities of Vitamin D from diet alone is difficult, especially a vegetarian diet.

Sunshine and Vitamin D Creation

Vitamin D is produced in the skin following direct exposure to sunlight. When the ultraviolet light from the sun connects with the skins precholesterol molecules (7-dehydrocholesterol) these molecules become provitamin D. This compound it then converted in the liver to 25hydroxyvitamin D (25[OH]D). In the kidneys this intermediate vitamin D is transformed into the 1,25 dihydroxycholecalciferol molecule (D3 calcitrol or 1,25-dihydroxyvitamin D (1,25{OH]2D), the biologically active form. Vitamin D-3 is delivered in the biologically active form.

Vitamin D-3 and Bone Health

Plays an important role in the treatment of osteoporosis and osteopenia.

Is an essential part of a bone health and bone loss prevention program.

Is a vital nutrient for healthy bone growth and development.

In its active hormone form increases calcium and phosphorus absorption and utilization in the intestines.

Helps maintain the balance of calcium and phosphorousin the blood and bone.

Promotes calcium deposits in the matrix of the bone.

Has revealed activity in the modulation of gene transcription directly affecting the bone. Vitamin D-3 supports bone strength and therefore reduces the risk of fractures.

Vitamin D-3 and Muscles, Mobility and Coordination

Research has found that strong muscles, good mobility and coordination have been associated with high levels of Vitamin D-3 in the blood. Vitamin D-3 deficiency is connected with muscle weakness. Studies have indicated that the muscle supporting action of vitamin D may contribute to a reduction in falls.

Vitamin D-3 and Pain

Several recent clinical studies have found that Vitamin D-3 deficiency is common in people with musculoskeletal pain. High dose Vitamin D-3 supplementation can reduce pain.

Vitamin D and Cancer Prevention

Studies have shown sufficient Vitamin D-3 levels are linked to a reduced risk of a variety of cancers. Vitamin D-3 is important for healthy cell growth and communication that reduces the risks for some types of cancer. The American Journal of Public Health February 2006, reports that researchers searched the Pub Med database and found 63 observational studies of vitamin D status in relation to cancer risk dating from 1966 to 2004. Thirty of those studies focused on vitamin D and colon cancer, 13 on breast cancer, 26 on prostate cancer, and 7 on ovarian cancer. In addition, several studies investigated whether mutations in vitamin D receptors are associated with an increased risk of cancer. After their review, the researchers concluded that the majority of the research found a protective relationship between sufficient vitamin D levels and lower risk of cancer. Most of the studies found that vitamin D could reduce cancer risk by up to 50 percent. Research on vitamin D and its cancer preventing properties is growing in volume and may indicate a need for adequate sunlight or supplementation.

Vitamin D and Autoimmune Disorders

Research suggests that Vitamin D-3 plays a role in immune function. Autoimmune disorders such as MS are much less prevalent in countries near the equator, where there is greater exposure to sunlight and greater production of vitamin D. Evidence suggests ultraviolet radiation (UVR) may play a protective role in three autoimmune diseases: multiple sclerosis, insulin-dependent diabetes mellitus and rheumatoid arthritis.

Conclusion

A nutrient that is as important to our physiology as vitamin D must be considered for any supplement program. Vitamin D3 is not prevalent in the diet. Supplementation is an important way to provide enough vitamin D-3 to support Optimal Health.

* These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.